A B C D E F G H I J K L M N O P Q R S T U V W X Y Z All
Makeshwar, Kshitij B.
- Niosome: a Novel Drug Delivery System
Authors
1 Department of Pharmaceutics, Vidyabharti College of Pharmacy, Camp Road, Amravati, Maharashtra 444602
Source
Asian Journal of Pharmaceutical Research, Vol 3, No 1 (2013), Pagination: 16-20Abstract
Niosomes are a novel drug delivery system, in which the medication is encapsulated in a vesicle. The vesicle is composed of a bilayer of non-ionic surface active agents and hence the name niosomes. Structurally, niosomes are similar to liposomes, in that they are also made up of a bilayer. However, the bilayer in the case of niosomes is made up of non-ionic surface active agents rather than phospholipids as seen in the case of liposomes. Most surface active agents when immersed in water yield micellar structures however some surfactants can yield bilayer vesicles which are niosomes. Niosomes may be unilamellaror multilamellar depending on the method used to prepare them. The niosomes are classified as a function of the number of bilayer (e.g. MLV, SUV) or as a function of size. (e.g. LUV, SUV) or as a function of the method of preparation (e.g.REV, DRV). Niosomes present a structure similar to liposome and hence they can represent alternative vesicular systems with respect to liposomes, due to the niosome ability to encapsulate different type of drugs within their multienvironmental structure. The technology utilized in niosomes is still greatly in its infancy, and already it is showing promise in the fields of cancer and infectious disease treatments.Keywords
Unilamellar, Multilamellar, Niosomes, Phospholipids, MultienvironmentalReferences
- Baillie AJ, Florence AT, Hume IR, Murihead GT, Rogerson A, The preparation and properties of niosomes-Nonionic surfactant vesicles,.J. Pharm. Pharmacol, 37, 2003, pp. 863-868.
- Chandraprakash KS, Udupa N, Umadevi P and Pillai GK, Indian J. Pharm. Sci., 54, 1992, pp. 197.
- www.pharmainfo.net/reviews/niosome-unique-drug delivery system
- Duijad RC, Manvi FC, Swati S and Rony M, Indian Drugs, 2008, pp. 713.
- Gadhiya P, Shukla S, Modi D, Bharadia P, A Review- Niosomes in Targeted Drug Delivery, International Journal for Pharmaceutical Research Scholars, 2, 2012, pp. 61.
- Pawar SD, Pawar RG, Kodag PP, Waghmare AS, Niosome: An Unique Drug Delivery System, International Journal of Biology, Pharmacy and Allied Sciences,3, 2012, pp 409-412.
- Khandare JN, Madhavi G, Tamhankar BM, Niosomes novel drug delivery system. The East Pharmacist. 37, 1994, pp. 61-64.
- Maver LD, Bally MB, Hope MJ, Cullis PR, Biochem. Biophys. Acta. 816, 1985, pp. 294-302.
- Blazek-Walsh AI, Rhodes DG, SEM imaging predicts quality of niosomes from maltodextrin-based proniosomes, Pharm. Res. 18, 2001, pp. 656-661
- Gadhiya P, Shukla S, Modi D, Bharadia P, A Review- Niosomes in Targeted Drug Delivery, International Journal for Pharmaceutical Research Scholars, 2, 2012.
- Akul Mehta, PharmaXChange_info - Articles – Niosomes
- Ruckmani K, Jayakar B and Ghosal SK, Drug Development and Industrial Pharmacy, 26, 2000, pp. 217-222.
- Baillie AJ, Coombs GH and Dolan TF, Non-ionic surfactant vesicles, niosomes, as delivery system for the anti-leishmanial drug, sodium stribogluconate, J. Pharm. Pharmacol., 38, 1986, pp. 502-505
- Conacher M, Alexanderand J, Brewer JM, Conacher M, and Alexander J, Niosomes as Immunological Adjuvants. In “Synthetic Surfactant Vesicles” (Ed. I.F. Uchegbu) International Publishers Distributors Ltd. Singapore, 2000, pp. 185-205.
- Azmin MN, Florence AT, Handjani-Vila RM, Stuart JB, Vanlerberghe, G and Whittaker JS, J. Pharm. Pharmacol., 37, 1985, pp, 237.
- Gadhiya P, Shukla S, Modi D, Bharadia P, A Review- Niosomes in Targeted Drug Delivery, International Journal for Pharmaceutical Research Scholars, 2, 2012, pp. 60.
- Pawar SD, Pawar RG, Kodag PP, Waghmare AS, Niosome: An Unique Drug Delivery System, International Journal of Biology, Pharmacy and Allied Sciences,3, 2012, pp. 412.
- Medicated Chewing Gum:Modern Approach to Mucosal Drug Delivery
Authors
1 Vidyabharti College of Pharmacy, Camp Road, Amravati, Maharashtra, 444602, IN
Source
Asian Journal of Research in Pharmaceutical Sciences, Vol 2, No 4 (2012), Pagination: 150-159Abstract
In recent years scientific and technological advancements have been made in the research and development of oral drug delivery system. It offers various advantages over conventional drug delivery systems. Unlike chewable tablets medicated gums are not supposed to be swallowed and may be removed from the site of application without resorting to invasive means.
Over the years, patient convenience and patient compliance-oriented research in the field of drug delivery has resulted in bringing out potential innovative drug delivery options. Out of which, medicated chewing gum (MCG) offers a highly convenient patient-compliant way of dosing medications, not only for special population groups with swallowing difficulties such as children and the elderly, but also for the general population, including the young generation. Medicated chewing gum delivery system is convenient, easy to administer - anywhere, anytime - and is pleasantly tasting making it patient acceptable. It offers a wide range of advantages that make it an excellent alternative. It can be used to prevent or cure the dental caries, smoking cessation, pain, obesity, xerostoma, acidity, diabetes etc.